1993 Nobel Prize Concept | Splicing Board Game | Science, Strategy, Fun Game Perfect for Family | Biology, DNA, RNA, Protein, Virus | Age 8+ | STEM Game

Description

• STEM BOARD GAME: play, socialize, and learn
• KNOWLEDGE 1: DNA, mRNA, protein, Molecular Biology, Cell Biology, Structural Biology, Central Dogma, Gene Regulation, Splicing, and Alternative Splicing; Virus, environment stress, antibody, stress resistance factor, neurons, metabolism, enzyme, energy production, mechanisms of diabetes and cancer, chemicals in daily life
• KNOWLEDGE 2: Introduce probability and randomness
• FUN 1: Easy to play - roll dice, draw cards, collect protein cards, win! Rich in strategies - alliance, trade, negotiate, lobby, attack, defend, and bluff
• FUN 2: Epic and magical - outer space planet setting with your favorite warrior, evil, and business roles. Make your choice!
• Number of players: 2-6

Players will roll dice, gather resource cards, form dynamic alliances, and create trading strategies to learn a complex but important biological process - mRNA splicing! Splicing board game features three kingdoms: Warrior, Evil, and Business. Each kingdom contends for dominance in the protein domain and represents a unique biological function within a living cell. (1) The glorious Warrior is composed of antibodies and stress resistance factors, which protect the cell from virus, bacteria and other environmental stress. (2) The devastating Evil is composed of viruses and stress, which interfere with biological functions. (3) The lucrative Business is composed of neuron investors and resource generators, which provide energy and signals to either the righteous Warrior or the wicked Evil. The game occurs in two phases. In phase I, players collect splicing scissor tools. In phase II, players collect protein cards to score by landing on the splicing cutting site to cut the intron, connect the exon on the mRNA. Players aim for 10 scores to win. In each phase, players can trade their cards with each other (i.e. form an antibody and neuron investor alliance), or they can sabotage one another's splicing process, like an evil virus. [Science background: in every living organism, DNA carries the genetic information. DNA is first transcribed into mRNA in order to decode the genetic information. Then, mRNA is translated into proteins. The genetic information is often interrupted by "junk" fragments (introns) in higher organisms, such as humans. Therefore, the initial transcribed mRNA contains both genetic fragments (exons) and "junk" fragments. Introns should be removed and exons should be joined in a process called mRNA splicing.]

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